The National Agency for Regional Health Services (Agenas) is a public agency established in 1993 as a technical-scientific body of the Ministry of Health. The main objectives of the Agency are to promote innovation and quality in healthcare, to perform comparative analysis of cost and effectiveness of healthcare services and to provide technical support to the Ministry of Health and to the Regions. The technical support provided by the Agency to the Ministry of Health and to the Regions has an essential role within our National Health Service which is exercised also by means of the scientific knowledge developed through specific research projects on healthcare services carried out by Agenas. The Agency runs analyses on healthcare models at different organizational levels (National, Regional, Local) and healthcare settings (community and primary care, prevention, hospital) as well as on the impact of these models and settings in terms of population equity, healthcare outcomes and population health and wellbeing. In this context, Agenas contributes to evaluate and to promote connections and integration between healthcare settings (such as hospital and community care) and the innovation of the organizational structures and its different components.