Readings on Frailty

Interested in frailty? Here are some informative readings:




2. Other Articles:

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WHAT IS FRAILTY ABOUT? punto interrogativo 6906191

Capanna, A., Scarcella, P., Gilardi, F., Mancinelli, S., Palombi, L., Marazzi, M.C., Riccardi, F. and Liotta, G. (2018) Sensitivity and Specificity of a Short Questionnaire to Screen Frailty in the Community-Dwelling Older Population. Advances in Aging Research, 7, 52-63. Link to the article

Clegg, A., Young, J., Iliffe, S., Rikkert, M. O. & Rockwood, K. (2013). Frailty in elderly people. Lancet (London, England), 381(9868), 752–62. Link to the article

Dent, E., Kowal, P. & Hoogendijk, E. O. (2016). Frailty measurement in research and clinical practice: A review. European Journal of Internal Medicine, 31, 3-10. Link to the article

Gwyther, H., Shaw, R., Dauden, E. A. J., D’Avanzo, B., Kurpas, D., Bujnowska-Fedak, M., ... & Holland, C. (2018). Understanding frailty: a qualitative study of European healthcare policy-makers’ approaches to frailty screening and management. BMJ open, 8(1). Link to the article

Ipsos, M. O. R. I. (2014). Understanding the lives of older people living with frailty–a qualitative investigation. London: Age UKLink to the report

Liotta, G., O’Caoimh, R., Gilardi, F., Proietti, M. G., Rocco, G., Alvaro, R., … & Marazzi, M. C. (2017) Assessment of frailty in community-dwelling older adults residents in the Lazio region (Italy): A model to plan regional community-based services. Archives of Gerontology and Geriatrics Volume 68, January–February 2017, Pages 1-7. Link to the article

Rodríguez-Mañas, L., Féart, C., Mann, G., Viña, J., Chatterji, S., Chodzko-Zajko, W., Vega, E. (2012). Searching for an operational definition of frailty: A Delphi method based consensus statement. The Frailty Operative Definition-Consensus Conference Project. The Journals of Gerontology: Series A, 68(1), 62-67. Link to the article

Schoenborn NL, Van Pilsum Rasmussen SE, Xue Q-L, Walston JD, McAdams-Demarco MA, Segev DL, Boyd CM: Older adults’ perceptions and informational needs regarding frailty. BMC Geriatrics 2018, 18(1):46. Link to the article









Bock, J., König, H., Brenner, H., Haefeli, W. E., Quinzler, R., Matschinger, H., Heider, D. (2016). Associations of frailty with health care costs – results of the ESTHER cohort study. BMC Health Services Research, 16(1). Link to the article

García-Nogueras, I., Aranda-Reneo, I., Peña-Longobardo, L. M., Oliva-Moreno, J. & Abizanda, P. (2016). Use of health resources and healthcare costs associated with frailty: The FRADEA study. The journal of nutrition, health & aging, 21(2), 207-214. Link to the article

Marazzi, M. C., Inzerilli, M. C., Madaro, O., Palombi, L., Scarcella, P., Orlando, S., Maurici, M., Liotta, G. (2015). Impact of the Community-Based Active Monitoring Program on the Long Term Care Services Use and In-Patient Admissions of the Over-74 Population. Advances in Aging Research. Link to the article   

Sirven, N.; Rapp, T. The cost of frailty in France. Eur. J. Health Econ. 2017, 18, 243–253. Link to the article     










exercise 21

Cadore, E. L., Rodríguez-Mañas, L., Sinclair, A. & Izquierdo, M. (2013). Effects of different exercise interventions on risk of falls, gait ability, and balance in physically frail older adults: A systematic review. Rejuvenation Research, 16(2), 105-114. Link to the article

Nagai K, Miyamato T, Okamae A, Tamaki A, Fujioka H, Wada Y, Uchiyama Y, Shinmura K, Domen K: Physical activity combined with resistance training reduces symptoms of frailty in older adults: A randomized controlled trial. Archives of Gerontology and Geriatrics 2018, 76:41-47. Link to the article  

Rogers NT, Marshall A, Roberts CH, Demakakos P, Steptoe A, Scholes S: Physical activity and trajectories of frailty among older adults: Evidence from the English Longitudinal Study of Ageing. PLoS ONE 2017, 12(2): e0170878. Link to the article

Susanto M, Hubbard RE, Gardiner PA: Twelve-Year Trajectories of Sitting Time are Associated With Frailty in Middle-Aged Women. American Journal of Epidemiology 2018:kwy111-kwy111. Link to the article

Theou, O., Stathokostas, L., Roland, K. P., Jakobi, J. M., Patterson, C. Vandervoort, A. A. & Jones, G. R. (2011). The Effectiveness of Exercise Interventions for the Management of Frailty: A Systematic Review. Journal of Aging Research, 2011, 1-19. Link to the article








balanced diet for men main image 700 350WHAT IS THE IMPORTANCE OF NUTRITION IN FRAILTY?

Bruyère, O., Cavalier, E., Buckinx, F. & Reginster, J. (2017). Relevance of vitamin D in the pathogenesis and therapy of frailty. Current Opinion in Clinical Nutrition and Metabolic Care, 20(1), 26-29. Link to the article

Cesari, M., Nobili, A. & Vitale, G. (2016). Frailty and sarcopenia: From theory to clinical implementation and public health relevance. European Journal of Internal Medicine, 35, 1-9. Link to the article

Goisser, S., Guyonnet, S. & Volkert, D. (2016). The role of nutrition in frailty: An overview. The Journal of Frailty & Aging, 5(2), 74–77. Link to the article

Laclaustra M, Rodriguez-Artalejo F, Guallar-Castillon P, Banegas JR, Graciani A, Garcia-Esquinas E, Ordovas J, Lopez-Garcia E: Prospective association between added sugars and frailty in older adults. The American Journal of Clinical Nutrition 2018, 107(5):772-779. Link to the article

León-Muñoz, L. M., Guallar-Castillón, P., López-García, E. & Rodríguez-Artalejo, F. (2014). Mediterranean diet and risk of frailty in community-dwelling older adults. Journal of the American Medical Directors Association, 15(12), 899-903. Link to the article

Lorenzo-López L, Maseda A, de Labra C, Regueiro-Folgueira L, Rodríguez-Villamil JL, Millán-Calenti JC: Nutritional determinants of frailty in older adults: A systematic review. BMC Geriatrics 2017, 17(108). DOI: Link to the article










BritainThinks (2015) Frailty: Language and Perceptions. A report prepared by BritainThinks on behalf of Age UK and the British Geriatrics Society. London: Age UK. Link to the report

Stop hand

Ministry of Health Spain (2014). Consensus document on frailty and falls prevention among the elderly. The prevention and health promotion strategy of the Spanish NHS. Available at:Stop hand. Link to the article

Morley, J. E., Vellas, B., Kan, G. A., Anker, S. D., Bauer, J. M., Bernabei, R., Walston, J. (2013). Frailty consensus: A call to action. Journal of the American Medical Directors Association, 14(6), 392-397. Link to the article

National Institute for Health and Care Excellence (NICE) (2015). Dementia, disability and frailty in later life – mid-life approaches to delay or prevent onset. NICE Guideline [NG16]. Link to the article

Puts, M. T., Toubasi, S., Andrew, M. K., Ashe, M. C., Ploeg, J., Atkinson, E., Mcgilton, K. (2017). Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a scoping review of the literature and international policies. Age and Ageing. Link to the article









Atkins JL, Delgado J, Pilling LC, Bowman K, Masoli JAH, Kuchel GA, Ferrucci L, Melzer D: Impact of Low Cardiovascular Risk Profiles on Geriatric Outcomes: Evidence From 421,000 Participants in Two Cohorts. The Journals of Gerontology: Series A 2018. Link to the article

Brunner EJ, Shipley MJ, Ahmadi-Abhari S, Valencia Hernandez C, Abell JG, Singh-Manoux A, Kawachi I, Kivimaki M: Midlife contributors to socioeconomic differences in frailty during later life: a prospective cohort study. The Lancet Public Health 2018, 3(7):e313-e322. Link to the article

Dani M, Owen LH, Jackson TA, Rockwood K, Sampson EL, Davis D: Delirium, Frailty, and Mortality: Interactions in a Prospective Study of Hospitalized Older People. The Journals of Gerontology: Series A 2018, 73(3):415-418. Link to the article

European Union (2017). The 2018 Ageing Report: Underlying assumptions & projection methodologies. Luxembourg: Publications Office of the European Union. European Commission, Directorate-General for Economic and Financial Affairs, Brussels. Link to the article

Gilardi, F., Scarcella, P., Proietti, M. G., Capobianco, G., Rocco, G., Capanna, A., ... & Liotta, G. (2018). Frailty as a predictor of mortality and hospital services use in older adults: a cluster analysis in a cohort study. European Journal of Public Health. Link to the article

Gale CR, Westbury L, Cooper C: Social isolation and loneliness as risk factors for the progression of frailty: the English Longitudinal Study of Ageing. Age and Ageing 2018, 47(3): 392–397. DOI: Link to the article

Gilbert T, Neuburger J, Kraindler J, Keeble E, Smith P, Ariti C, Arora S, Street A, Parker S, Roberts HC et al: Development and validation of a Hospital Frailty Risk Score focusing on older people in acute care settings using electronic hospital records: an observational study. The Lancet 2018, 391(10132):1775-1782. Link to the article

Hoeksema AR, Spoorenberg S, Peters LL, Meijer H, Raghoebar GM, Vissink A, Wynia K, Visser A: Elderly with remaining teeth report less frailty and better quality of life than edentulous elderly: a cross-sectional study. Oral Diseases (2017) 23, 526–536 doi:10.1111/odi.12644. Link to the article.

Hopwood, J., Walker, N., McDonagh, L., Rait, G., Walters, K., Iliffe, S., ... & Davies, N. (2018). Internet-Based Interventions Aimed at Supporting Family Caregivers of People With Dementia: Systematic Review. Journal of medical Internet research, 20(6), e216. Link to the article

Janssens, Barbara & Vanobbergen, Jacques & Petrovic, Mirko & Jacquet, Wolfgang & Schols, Jos M.G.A. & Visschere, Luc. (2017). The oral health condition and treatment needs of nursing home residents in Flanders (Belgium). Community dental health. 34. 143-151. 10.1922/CDH_4086Janssens09. Link to the article.

Janssens B, De Visschere L, van der Putten GJ, de Lugt-Lustig K, Schols JM, Vanobbergen J: Effect of an oral healthcare protocol in nursing homes on care staffs’ knowledge and attitude towards oral health care: a cluster-randomised controlled trial. Gerodontology. 2014 Nov 26. doi: 10.1111/ger.12164. Link to the article

Janssens, B., Petrovic, M., Jacquet, W., Schols, J. M. G. A., Vanobbergen, J., & De Visschere, L. (2017). Medication Use and Its Potential Impact on the Oral Health Status of Nursing Home Residents in Flanders (Belgium). Journal of the American Medical Directors Association, 18(9), 809.e1-809.e8. Link to the article.

Janssens B, Vanobbergen J, Lambert M, Schols JM, De Visschere L (2017) Effect of an oral healthcare programme on care staff knowledge and attitude regarding oral health: a non-randomised intervention trial. Clinical Oral Investigations 22:281–292. Link to the article

Janssens B, Vanobbergen J, Petrovic M, Jacquet W, Schols JM, De Visschere L (2018) The impact of a preventive and curative oral healthcare program on the prevalence and incidence of oral health problems in nursing home residents. PLoS ONE 13(6): e0198910. doi: 10.1371/journal.pone.0198910. Link to the article

Kamdem, B., Seematter-Bagnoud, L., Botrugno, F., & Santos-Eggimann, B. (2017). Relationship between oral health and Fried’s frailty criteria in community-dwelling older persons. BMC Geriatrics, 17(1), 174. Link to the article

Kojima G., Iliffe S., Jivraj S., Liljas A., Walters K. (2018). Does current smoking predict future frailty? The English longitudinal study of ageing. Age and Ageing, 47(1),126-131. Link to the article

Kojima, G., Iliffe, S., Jivraj, S., & Walters, K. (2016). Association between frailty and quality of life among community-dwelling older people: a systematic review and meta-analysis. J Epidemiol Community Health, 70(7), 716-721. Link to the article

Liotta G, Canhao H, Cenko F, Cutini R, Vellone E, Illario M, Kardas P, Poscia A, Dinis Sousa R, Palombi L, and Marazzi M C: Active Ageing in Europe: Adding Healthy Life to Years. Frontiers in Medicine, 30 April 2018. Link to the article

MacEntee I, Michael & Donnelly, Leeann. (2016). Oral health and the frailty syndrome. Periodontology 2000. 72. 135-141. 10.1111/prd.12134. Link to the article.

McDonagh J, Martin L, Ferguson C, Jha SR, Macdonald PS, Davidson PM, Newton PJ: Frailty assessment instruments in heart failure: A systematic review. European Journal of Cardiovascular Nursing 2018, 17(1):23-35. Link to the article

Redding, D., Gentry, T., Shand, J., Stuart, L. (2014) I'm Still Me…A Narrative for Coordinated Support for Older People. Link to the report

Soysal P, Veronese N, Thompson T, Kahl KG, Fernandes BS, Prina AM, Solmi M, Schofield P, Koyanagi A, Tseng P-T et al: Relationship between depression and frailty in older adults: A systematic review and meta-analysis. Ageing Research Reviews 2017, 36:78-87. Link to the article

Takada S, Yamamoto Y, Shimizu S, Kimachi M, Ikenoue T, Fukuma S, Onishi Y, Takegami M, Yamazaki S, Ono R et al: Association Between Subjective Sleep Quality and Future Risk of Falls in Older People: Results From LOHAS. The Journals of Gerontology: Series A 2018, 73(9):1205-1211. Link to the article

Walston J: Frailty Research Moves Beyond Risk Assessment. The Journals of Gerontology: Series A 2017, 72(7):915-916. Link to the article

World Health Organization (2015). World report on ageing and health. Luxembourg. Link to the article

World Health Organization (2017). Integrated Care for Older People (ICOPE). Guidelines on community-level interventions to manage declines in intrinsic capacity. Switzerland. Link to the article